In the world of brain-computer interfaces, Brainoware, a hybrid system that combines living brain cells with artificial intelligence (AI), has shown promising abilities in processing information and performing computing tasks. Guo and his team tested Brainoware’s capacity by tasking it with solving mathematical equations and recognizing speech patterns, proving that it could decode signals from audio recordings, albeit with less accuracy than artificial neural networks. While this breakthrough showcases the potential of brain organoids, it also raises questions about their long-term information storage and multifunctional learning capabilities. Despite the challenges, this research serves as a significant step forward in demonstrating the capabilities of brain organoids in collaboration with AI.