Life span increases in mice when specific brain cells are activated

Key Points:

  • Researchers at Washington University School of Medicine in St. Louis have identified a critical communication pathway between the brain and the body’s fat tissue in mice, which influences aging and life span.
  • Activating specific neurons in the brain’s hypothalamus triggers the release of energy from fat tissue, leading to delayed aging and longer life spans in mice.
  • The study’s findings could pave the way for future interventions that aim to maintain the brain-fat tissue feedback loop, potentially offering insights into combating aging-related health issues in humans.

Summary:

Researchers at Washington University School of Medicine in St. Louis have discovered a crucial feedback loop between the brain and fat tissue that has a significant impact on aging in mice. The study identifies specific neurons in the hypothalamus that, when activated, signal the body’s fat tissue to release energy, which results in delayed aging and longer life spans in mice. This groundbreaking research could lead to interventions that maintain this feedback loop and potentially slow the effects of aging in humans.

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